For which of the following foods is a 95% positive predictive value for serum IgE established?

Prepare for the ACAAI Board Exam. Utilize flashcards and comprehensive multiple-choice questions, equipped with hints and detailed explanations. Ace your allergy and clinical immunology exam efficiently.

The choice highlighting egg, milk, peanut, and fish as having a 95% positive predictive value for serum IgE is correct because extensive clinical and laboratory research has demonstrated a strong correlation between serum specific IgE levels and clinical reactivity to these foods. In cases of food allergies, particularly those involving cow's milk, hen's egg, peanut, and certain fish, high IgE levels in serum predict a high likelihood of an allergic reaction when the individual is exposed to the allergenic food.

This high predictive value is essential in clinical practice as it helps clinicians make informed decisions about diagnosis and management of food allergies. The data supporting this comes from numerous studies that have established thresholds for IgE levels that correlate strongly with the presence of clinical allergies to these specific foods.

In contrast, the other options encompass food allergens which, while they may provoke allergic reactions in some individuals, do not universally meet the same established predictive value for serum IgE. This variance highlights the importance of understanding specific food allergy profiles for accurate diagnosis and appropriate treatment protocols.

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