In which patient population is Babesia infection typically more severe?

Babesia infection, caused by the protozoa of the genus Babesia, is known to be particularly severe in immunocompromised individuals. This population includes those with weakened immune systems due to conditions such as HIV/AIDS, cancer, or those undergoing immunosuppressive therapy. In healthy individuals, Babesia may cause mild to moderate symptoms; however, in immunocompromised patients, the lack of a robust immune response can lead to more severe illness, complications, and increased mortality.

The severity of the infection in this population is attributed to their reduced ability to control the parasite, leading to more significant hemolysis, potential organ failure, and complications such as respiratory distress syndrome. The other groups listed, while they may have unique considerations or risks, do not typically experience the same level of severity in response to Babesia infections as immunocompromised individuals do.