What CD molecules are part of the BCR coreceptor?

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The B cell receptor (BCR) is a critical component of the adaptive immune response, allowing B cells to recognize specific antigens. The coreceptors that are associated with the BCR are vital for the effective activation and signaling of B cells upon antigen binding.

The correct set of molecules involved in the BCR coreceptor includes CD21, CD19, and CD81. These molecules play specific roles in B cell activation:

  • CD21, also known as complement receptor 2 (CR2), enhances signaling by binding to complement-coated antigens, facilitating the recognition and activation of B cells.

  • CD19 acts as a signaling molecule critical for B cell activation and is a significant part of the BCR complex. It transmits signals that strengthen the B cell response.

  • CD81, also known as TAPA-1, associates with CD19 to form a complex that is necessary for efficient BCR-mediated signaling and is essential for maintaining B cell longevity and function.

Together, these molecules facilitate a stronger and more effective response to antigens, making them integral to B cell function in the immune system. The other choices include various combinations of molecules, but they do not constitute the coreceptors specific to the BCR. Therefore, the combination of CD

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