What cell surface marker does rhinovirus bind to?

Rhinoviruses primarily attach to specific receptors on the surface of host cells to initiate infection, and one of the key receptors they bind to is known as intercellular adhesion molecule-1 (ICAM-1), which is identified by the cell surface marker CD54. This interaction is crucial for viral entry into the host cells, allowing the rhinovirus to exploit the cellular machinery for replication.

The cell's surface markers serve various functions, but in the context of rhinovirus, CD54 plays a pivotal role as a receptor that can mediate the virus's ability to infect. Understanding the relevance of CD54 in the rhinoviral life cycle is essential for developing therapeutic strategies aimed at blocking this interaction, potentially offering a way to prevent or treat infections caused by this common virus.