What is the main source of Factor D?

Factor D is primarily produced in adipose tissue. This enzyme plays a critical role in the complement system, specifically in the activation of the alternative pathway. Adipose tissue is known to have a significant impact on various biochemical processes, including inflammation and immune response, which contributes to the production of complement factors like Factor D.

While the liver is involved in the production of many plasma proteins and factors crucial for coagulation and immune function, it is not specifically the main source for Factor D. Bone marrow and the spleen also have roles in hematopoiesis and immune regulation, but they do not play a significant direct role in the production of Factor D. Thus, the unique association between Factor D production and adipose tissue emphasizes the importance of this tissue in immune response and complement activation.