What is the major mouse allergen and its source?

Prepare for the ACAAI Board Exam. Utilize flashcards and comprehensive multiple-choice questions, equipped with hints and detailed explanations. Ace your allergy and clinical immunology exam efficiently.

The major mouse allergen is indeed Mus m 1, which originates primarily from male mouse urine. This allergen is significant because it is highly potent and can trigger allergic reactions in sensitive individuals. Mice produce a variety of proteins in their urine, and Mus m 1 is one of the key components that can lead to sensitization and allergic responses in humans.

In contrast to the other options, which represent allergens from different sources (dust mites, cats, and dogs), Mus m 1 is specifically associated with mice, making it particularly relevant for individuals exposed to mouse allergens in homes, laboratories, or other environments where mice are present. Understanding the source of Mus m 1 helps in managing allergies and reducing exposure to this potent allergen.

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