When interpreting food-specific serum IgE levels, which food allergies are significantly influenced by age?

The correct answer pertains to milk and egg allergies, which are notably influenced by age in terms of their prevalence and resolution. In infants and young children, milk and egg allergies are quite common, but many children tend to outgrow these allergies as they age. This transition is particularly observed by the time they reach school age, where the incidence of milk and egg allergies significantly decreases.

The underlying reason for this age-related change lies in the maturation of the immune system, which continues to develop during early childhood. As children grow, their immune system often becomes less reactive to common allergens like milk and eggs, leading to tolerance. Therefore, understanding the age-related dynamics of these allergies is crucial for clinical management and for guiding parents in dietary practices.

On the other hand, while certain food allergies such as tree nuts, fish, shellfish, and peanuts can also be found in children, they often persist into adulthood. Unlike milk and egg allergies, these allergies are less likely to resolve with age, which is why they are not as significantly influenced by it when compared to milk and egg allergies.