Which complement receptor is identified as CD11c/CD18?

CD11c/CD18 corresponds to CR4, which is a complement receptor involved in the immune response. It plays a crucial role in the adherence and phagocytosis of pathogens by immune cells, particularly dendritic cells and macrophages.

Complement receptors are important for recognizing complement-coated pathogens, facilitating their clearance from the body. CD11c/CD18, specifically as part of CR4, is necessary for various immune functions, including the activation and regulation of immune responses.

The other complement receptors mentioned, such as CR1, CR2, and CR3, each have distinct roles and combinations of subunits. For example, CR1 is involved in the regulation of complement activation and opsonization, CR2 has roles in B cell activation particularly related to immune response, and CR3 is primarily associated with phagocytosis and cellular adhesion but is represented by the CD11b/CD18 complex instead of CD11c/CD18. Understanding these distinctions helps clarify why CD11c/CD18 identifies as CR4, emphasizing its specific contributions within the immune system.