Which condition is characterized by recurrent respiratory infections and associated with cartilage anomalies?

Prepare for the ACAAI Board Exam. Utilize flashcards and comprehensive multiple-choice questions, equipped with hints and detailed explanations. Ace your allergy and clinical immunology exam efficiently.

The condition characterized by recurrent respiratory infections and associated with cartilage anomalies is Kartagener's syndrome. This syndrome is part of a group of disorders known as primary ciliary dyskinesia (PCD), where the cilia, which are tiny hair-like structures that line the respiratory tract, are either absent or do not function properly. This dysfunction causes inadequate clearance of mucus and pathogens from the airways, leading to recurrent respiratory infections.

Additionally, individuals with Kartagener's syndrome often exhibit specific anatomical anomalies, most notably situs inversus, where the internal organs are mirrored from their normal positions. The defect in ciliary function contributes not only to respiratory infections but can also lead to issues with the development of cartilage and other connective tissues in the body, causing further complications.

Understanding this condition's relation to both recurrent infections and potential cartilage abnormalities helps in recognizing the importance of ciliary function in respiratory health.

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