Which inhaled corticosteroid is preferred for use during pregnancy?

Budesonide is the preferred inhaled corticosteroid for use during pregnancy due to its safety profile. Research indicates that budesonide has a lower systemic bioavailability compared to other corticosteroids, which may reduce the potential for adverse effects on the fetus. It is commonly used for managing asthma during pregnancy because it has been studied more extensively in this population and is considered safer.

Additionally, guidelines from respected health organizations recommend budesonide as the first-line inhaled corticosteroid for pregnant patients requiring asthma treatment, as it is the only inhaled corticosteroid studied in randomized controlled trials specifically during pregnancy. This evidence supports the decision to use budesonide over alternatives like beclomethasone, fluticasone, or triamcinolone, which have not been studied as thoroughly in the context of pregnancy, leading to more uncertainty regarding their safety.