Which occupational asthma agent is associated with smoking?

The association of platinum with occupational asthma, particularly in the context of smoking, is well-documented. Workers exposed to platinum compounds, particularly in industries such as jewelry manufacturing and metal refining, have been shown to develop allergic reactions leading to asthma. The relevance of smoking arises because smokers are often at an increased risk for respiratory issues, potentially exacerbating the effects of exposure to platinum.

Additionally, platinum salts can elicit a Type I hypersensitivity response, and when combined with the deleterious effects of smoking, which can impair lung function and increase airway inflammation, the overall risk for developing occupational asthma is heightened. This highlights how dual exposure—both to the occupational agent (platinum) and the risk factor (smoking)—can significantly contribute to respiratory health issues among certain populations.