Which vaccine is known to potentially contain up to 5% yeast protein?

The Hepatitis B Virus Vaccine is known to potentially contain up to 5% yeast protein because it is produced using recombinant DNA technology, which involves yeast cells (Saccharomyces cerevisiae) as a host for the expression of the hepatitis B surface antigen (HBsAg). This method of production can lead to residual yeast protein in the final vaccine product. The presence of yeast protein is significant for individuals with allergies or sensitivities to yeast, making awareness of this component important in clinical practice.

Other vaccines listed, such as the Influenza Virus Vaccine, Measles, Mumps, Rubella Vaccine, and Varicella Vaccine, are not associated with yeast proteins to the same extent and are produced using different methods that do not involve yeast as a significant component. Therefore, they do not pose the same concern for individuals with yeast allergies.